CyPA™-ET [Liquid]
CyPA™-PW[Powder]
CyPA™ paves the way for enhancing skin elasticity and removing wrinkles
Cyclic lysophosphatidic acid (CyPA) is a novel lysophospholipid with a highly unique structure. The phosphate groups form a ring through ester bonds within the molecules. CyPA™ is a biological component present in trace quantities in human serum and tears. Many reports have been issued on the functions of CyPA™, ranging from anti-cancer activity to nerve regeneration and more.
In addition, CyPA™ has been found to have numerous positive effects on skin treatment. Accordingly, we have been manufacturing CyPA™ from soybean lysolecithin through an enzyme process, and we have applied it to cosmetics.

1. Features
- Function
Shrink hair follicles, moisturize skin, and improve skin elasticity and wrinkles
Epidermis | Dermis |
---|---|
Enhancement of hyaluronan production enzyme expression | Enhancement of hyaluronan production |
Enhancement of transglutaminase expression | Strengthening of actin filament |
Enhancement of ceramide production | Strengthening of focal adhesion |
Enhancement of aquaporin 3 expression | Collagen-gel (dermis model) contraction |

2. Specification
INCI | content (%) |
---|---|
CYCLIC LYSOPHOSPHATIDIC ACID | 20.0 |
ALCOHOL | 40.0 |
WATER | 40.0 |
INCI | content (%) |
---|---|
CYCLIC LYSOPHOSPHATIDIC ACID | 50.0 |
CYCLODEXTRIN | 50.0 |
3. Functionality
1. Effects on epidermal keratinocytes

2. Effects on dermal fibroblasts

4. Technical data
- CyPA™-ET, CyPA™-PW Technical data (PDF: 98KB)