CyPA-ET [Liquid]
CyPA-PW[Powder]

CyPA paves the way for enhancing skin elasticity and removing wrinkles

Cyclic lysophosphatidic acid (CyPA) is a novel lysophospholipid with a highly unique structure. The phosphate groups form a ring through ester bonds within the molecules. CyPA is a biological component present in trace quantities in human serum and tears. Many reports have been issued on the functions of CyPA, ranging from anti-cancer activity to nerve regeneration and more.
In addition, CyPA has been found to have numerous positive effects on skin treatment. Accordingly, we have been manufacturing CyPA from soybean lysolecithin through an enzyme process, and we have applied it to cosmetics.

1. Features

  • Function
    Shrink hair follicles, moisturize skin, and improve skin elasticity and wrinkles
Epidermis Dermis
Enhancement of hyaluronan production enzyme expression Enhancement of hyaluronan production
Enhancement of transglutaminase expression Strengthening of actin filament
Enhancement of ceramide production Strengthening of focal adhesion
Enhancement of aquaporin 3 expression Collagen-gel (dermis model) contraction

2. Specification

CyPA-ET
INCI content (%)
CYCLIC LYSOPHOSPHATIDIC ACID 20.0
ALCOHOL 40.0
WATER 40.0
CyPA-PW
INCI content (%)
CYCLIC LYSOPHOSPHATIDIC ACID 50.0
CYCLODEXTRIN 50.0

3. Functionality

1. Effects on epidermal keratinocytes

2. Effects on dermal fibroblasts

4. Technical data

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