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 HOME > NOF Businesses > Research & Development > Recent Key Products > Polyethylene-glycol (PEG) modifier SUNBRIGHT®
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Recent Key Products


PEG Modifier SUNBRIGHT


   
Background
In recent years, there has been active research into drug delivery systems (DDS) in the medical field. DDS enable the delivery of drugs that may have strong therapeutic benefits, but that could become poisonous if not delivered to the designated area or lose stability if they remain in the bloodstream. By using polymer molecules and other devices, DDS can accurately deliver the drug to the target area, thereby ensuring drug efficacy and allowing the use of lower doses to achieve the desired effect.

Characteristics
NOF's polyethylene-glycol (PEG) SUNBRIGHT®, incorporating functional groups to help it fuse with the drug, is gaining worldwide interest as a DDS polymer molecule.

The PEG used in SUNBRIGHT® is also called a drug modifier. Because it is injected into the body, advanced polymerization refining technology is needed to ensure the PEG is highly pure and contains few by-products, while the polymer molecules themselves must be uniform in size. NOF is the only company in the world currently capable of producing PEG.



Three main benefits are derived from modifying the drug with SUNBRIGHT®:
1. Improved in vivo stability
2. Enhanced antigenic characteristics
3. Addition of water solubility and other properties


Inquiries
DDS Development Division
Tel. +81-3-5424-6741
Fax. +81-3-5424-6769

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