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Background
The corneal layer of the epidermis is made up of flat corneocytes and intercellular fat that fills the spaces between strata. Ceramide (a type of glycolipid), the primary component of this fat, has many roles. Ceramide holds corneocytes together, serves as a barrier to harmful external substances, helps skin retain moisture, and enables skin to retain its elasticity. Overall, ceramide plays a vital part in all aspects of protecting and preserving skin by keeping it hydrated.
Rough skin is caused by aging as well as a number of other effects, such as dryness, ultraviolet rays and stress. In addition, a decline in the volume of ceramide, one of the components of the skin's corneal layer, is recognized as a cause of roughness.
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