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Product Information


MPC monomer (biocompatible material)


MPC (2-methacryroyloxyethylphosphorylcholine)

MPC (2-Methacryloyloxyethylphosphorylcholine) monomer has a polymerizable structure that is similar to the human cell membrane and it is a remarkable, new biocompatible material that has a high compatibility with living organs and tissues. NOF became the first company in the world to build a commercial plant capable of producing such MPC monomers and LIPIDURE® (polymers).

MPC is a polymerizable compound (monomer) and NOF has developed the LIPIDURE® series as products related to MPC monomer.

The advantages of LIPIDURE® in each field are shown below.

Additional information

Products for eye care


NOF has developed an enzyme-based, all-in-one cleaning and storage solution containing LIPIDURE® for hard contact lenses that can be handled easily and supplies this product to a number of contact lens manufacturers.
LIPIDURE® stabilizes the enzyme that breaks down the protein deposits on dirty lenses, giving the solution its excellent cleaning property.

Contact lenses washed with LIPIDURE® are comfortable to wear and the LIPIDURE® solution also prevents dry eyes, making it a remarkable product that is highly attracts the attention in the eye care field.

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Products for oral care and topical use


In addition to being tasteless and odorless, LIPIDURE® can also suppress bitterness. Furthermore, LIPIDURE® has the ability to prevent the adhesion of bacteria that cause dental caries and can protect mucosal cell from the toxicity of periodontal disease bacteria.
These characteristics make LIPIDURE® the perfect material to include in oral care products such as mouth wash.
Since LIPIDURE® has an excellent moisturizing effect and the ability to protect the skin from irritants, it is also used in products applied directly to the skin.

Additional information

Medical device products


LIPIDURE® is a biocompatible material with high functionality that was developed based on the cell membrane composing the human body.

Coating a medical device with LIPIDURE® makes it biocompatible.

Characteristics of LIPIDURE® for Medical Devices
  • Forming a biocompatible surface with high functionality
  • Forming a surface that suppresses blood components, protein and cell adsorption
  • Forming a surface that suppresses protein denaturation and cell activation
  • Forming a surface that is hydrophilic and is highly lubricious
  • Forming a surface that is appropriate for floating culture and the formation of spheroid (cell aggregate)
Additional information
Coated the screws inside an artificial heart with LIPIDURE<sup>®</sup>
Source: Data from Prof. Yamazaki of Tokyo Womens Medical University and Sun Medical Technology Research Corp.

Diagnostic reagents


BIOLIPIDURE® series are a new type of additives for diagnostic reagents made from MPC monomer containing a phosphorylcholine group, which in turn contains a polar group of phospholipid.
Since the phosphorylcholine group has a structure similar to the polar group of phospholipids composing the cell membrane, BIOLIPIDURE® can suppress protein adsorption and protein denaturation well.
These properties can also promote enzyme reaction and antigen-antibody reaction.
BIOLIPIDURE® can be used as additives and diluent of diagnostic reagents, sample diluent, and third reagents. With BIOLIPIDURE®, it is possible to suppress the carryover effect of reagent ingredients and sample ingredients (suppress non-specific adsorption), stabilize protein, promote reactions (sensitizing effect), and improve the ratio adjustment and dispersion of microparticles.
BIOLIPIDURE® series is a wholly synthesized macromolecule, so it is free from biohazard risk and has little lot-to-lot variations.

Additional information

Oxidative stress antibody products


Many diseases related to aging such as arterial sclerosis, cancer and diabetes are believed to arise from oxidative stress.
NOF currently supplies the following antibody products: genetic stress marker anti-8-OHdG, lipid stress markers anti-acrolein (ACR), anti-malondialdehyde (MDA), anti-crotonaldehyde (CRA), and sugar stress marker anti-methylglyoxal (MG). These markers are employed in the research of age-related diseases and lifestyle-related disorders, and are also expected to play a part in the development of foods that help control harmful active oxygen in the body, or anti-aging oxidants.

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