Rough skin tests were performed using LIPIDURE®. Application of 7.5% sodium dodecyl sulfate solution (SDS) to the skin for a week causes desquamation, edema, and erythema. However, these symptoms can be prevented by applying LIPIDURE® simultaneously. Application of SDS to a culture of human normal keratinocyte induces production of IL-1α, an inflammatory cytokine. LIPIDURE® decreases the amount of IL-1α production and reduces the damage to cells caused by SDS.
When shampooed hair was tied up, the surface of the cuticle was lifted. On the other hand, the surface of the cuticle treated with LIPIDURE® did not lift. (Photo 3)
LIPIDURE® is effective for protecting the skin and hair, and makes them smooth.